Related non-peptides & cofactors
Compounds often catalogued alongside peptides.
| Compound | Research area | Residues | Highest evidence | Sequence |
|---|---|---|---|---|
| 5-Amino-1MQ | Related non-peptides & cofactors | — | Preclinical (animal and cell studies) | |
| Glutathione | Related non-peptides & cofactors | 3 | Early clinical studies | ECG–OH |
| NAD+ | Related non-peptides & cofactors | — | Early clinical studies |
- 5-Amino-1MQ
5-Amino-1MQ is not a peptide; it is a small-molecule quaternary quinolinium compound that inhibits the enzyme nicotinamide N-methyltransferase (NNMT). It has been studied in cell and rodent models of obesity and metabolism.
- Glutathione
Glutathione is a tripeptide (γ-Glu-Cys-Gly) found in nearly all cells, where it acts as a major antioxidant and redox buffer. Its glutamate is linked through the side-chain gamma carboxyl, an unusual, non-standard peptide bond.
- NAD+
NAD+ (nicotinamide adenine dinucleotide) is not a peptide; it is a dinucleotide coenzyme essential for redox metabolism and a substrate for sirtuins, PARPs and CD38. It is studied in aging and metabolic research.